Population Genetics

Population Graph Stability

A population graph is a network structure based upon inter-stratum conditional genetic covariance (see Dyer & Nason 2004 for a more complete discussion). In this context, it is often of interest to know the statistical stability of your loci in determining the topology you see in the popgraph. Here is a way to subsample the loci you have and identify the extent to which you are asymptotically estimating a stable topology.

STRUCTURE on OSX

The program STRUCTURE is an ubiquitous feature of many population genetic studies these days—if it is appropriate is another question. Today, while covering model based clustering in population genetics, we ran into a problem where STRUCTURE was unable to run and the OS said it was Corrupted and should be thrown away. Jump below for our fix, it really is an easy one.

Inbreeding (Positive Assortative Mating based on Genotype)

Here are the slides for the lecture on inbreeding.

Effective Population Size

How big is the data set you are analyzing? Apparently it depends on how you count…

Chapter 2: Hardy-Weinberg Equilibrium

Here are the online presentations for Chapter 2: Hardy Weinberg Equilibrium from the upcoming text, Applied Population Genetics. More information on this text can be found here.

Applied Population Genetics Textbook Release

I will be posting portions of all 10 chapters of my upcoming textbook, Applied Population Genetics, as early draft chapters to this website over the spring semester.

Your relatives.

Ran across this great image from lifehacker. Perfect for your genetics and population genetic pedigree analyses.